There are two main types of T cell modulators:
- T cell agonists: These are substances that activate T cells, which can help stimulate the immune system to fight cancer or infections. Examples of T cell agonists include checkpoint inhibitors, which block the "brakes" on the immune system that can prevent T cells from attacking cancer cells.
- T cell antagonists: These are substances that suppress the function of T cells, which can help prevent the immune system from attacking healthy tissues in cases of autoimmune diseases or organ transplant rejection. Examples of T cell antagonists include cyclosporine and tacrolimus, which are commonly used in transplant medicine to prevent rejection.
