Cushing syndrome

There are several causes of Cushing syndrome, including:

• Overproduction of cortisol by the adrenal glands
• Tumors in the pituitary gland, which can cause the adrenal glands to produce too much cortisol
• Long-term use of corticosteroid medications, such as prednisone

Symptoms of Cushing syndrome can include:

• Weight gain, particularly in the abdomen and face
• High blood pressure
• Muscle weakness
• Fatigue
• Mood changes, such as depression or anxiety
• Increased thirst and urination
• Women may experience irregular menstrual periods and excess hair growth

Diagnosis of Cushing syndrome typically involves blood and urine tests to measure cortisol levels, as well as imaging studies to identify any tumors in the pituitary gland or adrenal glands. Treatment depends on the underlying cause of the condition and may include surgery, radiation therapy, or medication to reduce cortisol production.